Carlo Aleci, MD, Ph.D
Ophthalmology Research: an International Journal, 13(1):16-24, 2020.
The damage to the visual field is the main outcome of glaucoma. Basically, there are two different approaches to establish the rate of the functional loss in this clinical condition: event-based analysis and trend-based analysis. The event-based analysis, that relies on the occurrence of preestablished events to detect the progression of the visual field damage, cannot quantify the decay rate of sensitivity. In turn, the trend-based analysis, that aims to measure the rate of progression according to linear regression models, requires a long follow-up. Despite considerable effort, there is still no consensus on the optimal procedure, and a gold standard is still missing. This paper provides a quick overview of the topic as a tribute to the researchers engaged in this field.
Keywords: Glaucoma; visual field; perimetry; progression; AGIS; CTGS; GSS; point-wise regression.